my son 8 years outmoded, he is poor within schoo performence, his pronounciation is also not clear as the regular child hold. the doctor diagonsis as Frontal Lobe Atrophy by CT scan but he did not clarify that it irreversible defact or reversible defact.please advocate me clearly roughly this deises & who is wright man to consult, what is treatment?
Answers:
I imagine it is unusual to see this condition contained by such a immature individual. I would give somebody a lift him in half a shake to a neurologist for further evaluation, and to seize an assessment roughly potential treatment and long permanent status outlook.
As some surroundings info for you, in 1982, Mesulam reported 6 patients near progressive aphasia, leisurely worsening over various years, who did not develop a more generalized dementia. Since Mesulam's publication, numerous other cases hold be reported. This disorder, which is currently term primary progressive aphasia (PPA), has gain taking up as a syndrome. Rarely, cases of isolated right frontal or temporal degeneration own be reported. These patients experience bomb to make out own flesh and blood member (prosopagnosia), let-down to remember topographic relationships, and similar disorders.
In England, cases of frontal lobe dementia hold be described next to progressive dysfunction of the frontal lobes. In a series of skin reports, Neary and Snowden outlined a syndrome beside initial symptoms that be suggestive of psychiatric condition. However, the following frontal lobe behavioral abnormality appeared over time: disinhibition, impulsivity, impersistence, inertia, loss of social awareness, disregard of personal hygiene, mental rigidity, stereotyped behavior, and utilization behavior (ie, proclivity to pick up and rub any be reluctant surrounded by the environment). These descriptions included discourse abnormality such as reduced speech output, mutism, echolalia, and perseveration.
In recent years, the condition described contained by the North American literature as PPA and that described surrounded by the European literature as frontal dementia own be combined below the diagnosis frontotemporal dementia (FTD).
Some North American authors own included below the FTD category cases surrounded by which artistic and musical ability own in reality emerge after the start of the weakness, usually surrounded by association near progressive verbal communication impairment.
Pathophysiology: The precise molecular cause of FTD and PPA remain cagey. Considerable progress have be made beside good opinion to mutations within the tau protein that result in neurofibrillary tangle and neuronal degeneration. Other cases do not appear to own tau pathology and are more related to ubiquitin staining in the apprehensive system.
Frequency:
In the US: The exact prevalence of FTD is unknown. Some series base on brain pathology own estimated that FTD comprises as tons as 10% of cases of dementia. In the United States, estimates are across the world lower.
Internationally: Studies on FTD from Lund, Sweden, and Manchester, England, estimate that FTD accounts for approximately 8% of patients next to dementia. Probably the most accurate information comes from a Dutch study by Stevens et al, who reported 74 cases in a population of 15 million (ie, 5 cases per million). Among those aged 60-70 years, the prevalence be 28 cases per 100,000.
Mortality/Morbidity: FTD, similar to adjectives dementing illnesses, shortens enthusiasm expectancy. The exact influence on mortality is unknown. The rate of progression is unsettled. Patients next to associated motor neuron disease tend to hold much shorter life span expectancy.
The average age of birth is younger than that of Alzheimer disease (AD).
The rate of progression from focal presentation to a more generalized dementia vary. Some patients experience merely aphasia for period exceeding 10 years, while others progress to dementia in a few years.
In a subset of cases, motor neuron disease develops. This subgroup have a sophisticated mortality rate from FTD than other artificial patients. Swallowing difficulty and aspiration pneumonia are especially adjectives surrounded by this subgroup of patients, but even patients beside PPA can develop dysphagia past due surrounded by the course of the condition.
Sex: FTD can develop at almost any age within any sexual category. The most complete review, compiled by Westbury and Bub, investigated 112 published cases prior to 1997; the series included 66% males and 34% females.
Age: FTD is unanimously believed to present at an in advance age than AD. In the 1997 review by Westbury and Bub, the imply age of birth be 59 years. The mode age be 64 years.
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Answers:
I imagine it is unusual to see this condition contained by such a immature individual. I would give somebody a lift him in half a shake to a neurologist for further evaluation, and to seize an assessment roughly potential treatment and long permanent status outlook.
As some surroundings info for you, in 1982, Mesulam reported 6 patients near progressive aphasia, leisurely worsening over various years, who did not develop a more generalized dementia. Since Mesulam's publication, numerous other cases hold be reported. This disorder, which is currently term primary progressive aphasia (PPA), has gain taking up as a syndrome. Rarely, cases of isolated right frontal or temporal degeneration own be reported. These patients experience bomb to make out own flesh and blood member (prosopagnosia), let-down to remember topographic relationships, and similar disorders.
In England, cases of frontal lobe dementia hold be described next to progressive dysfunction of the frontal lobes. In a series of skin reports, Neary and Snowden outlined a syndrome beside initial symptoms that be suggestive of psychiatric condition. However, the following frontal lobe behavioral abnormality appeared over time: disinhibition, impulsivity, impersistence, inertia, loss of social awareness, disregard of personal hygiene, mental rigidity, stereotyped behavior, and utilization behavior (ie, proclivity to pick up and rub any be reluctant surrounded by the environment). These descriptions included discourse abnormality such as reduced speech output, mutism, echolalia, and perseveration.
In recent years, the condition described contained by the North American literature as PPA and that described surrounded by the European literature as frontal dementia own be combined below the diagnosis frontotemporal dementia (FTD).
Some North American authors own included below the FTD category cases surrounded by which artistic and musical ability own in reality emerge after the start of the weakness, usually surrounded by association near progressive verbal communication impairment.
Pathophysiology: The precise molecular cause of FTD and PPA remain cagey. Considerable progress have be made beside good opinion to mutations within the tau protein that result in neurofibrillary tangle and neuronal degeneration. Other cases do not appear to own tau pathology and are more related to ubiquitin staining in the apprehensive system.
Frequency:
In the US: The exact prevalence of FTD is unknown. Some series base on brain pathology own estimated that FTD comprises as tons as 10% of cases of dementia. In the United States, estimates are across the world lower.
Internationally: Studies on FTD from Lund, Sweden, and Manchester, England, estimate that FTD accounts for approximately 8% of patients next to dementia. Probably the most accurate information comes from a Dutch study by Stevens et al, who reported 74 cases in a population of 15 million (ie, 5 cases per million). Among those aged 60-70 years, the prevalence be 28 cases per 100,000.
Mortality/Morbidity: FTD, similar to adjectives dementing illnesses, shortens enthusiasm expectancy. The exact influence on mortality is unknown. The rate of progression is unsettled. Patients next to associated motor neuron disease tend to hold much shorter life span expectancy.
The average age of birth is younger than that of Alzheimer disease (AD).
The rate of progression from focal presentation to a more generalized dementia vary. Some patients experience merely aphasia for period exceeding 10 years, while others progress to dementia in a few years.
In a subset of cases, motor neuron disease develops. This subgroup have a sophisticated mortality rate from FTD than other artificial patients. Swallowing difficulty and aspiration pneumonia are especially adjectives surrounded by this subgroup of patients, but even patients beside PPA can develop dysphagia past due surrounded by the course of the condition.
Sex: FTD can develop at almost any age within any sexual category. The most complete review, compiled by Westbury and Bub, investigated 112 published cases prior to 1997; the series included 66% males and 34% females.
Age: FTD is unanimously believed to present at an in advance age than AD. In the 1997 review by Westbury and Bub, the imply age of birth be 59 years. The mode age be 64 years.